Following discussions of the plans laid out in Prime Minister's Questions, the aye's won this afternoon's vote with a majority of 478 – 516 voted in favour of the lockdown, while 38 voted against it.
Both Peterborough MP Paul Bristow and MP for North West Cambridgeshire Shailesh Vara voted in favour of the lockdown.
MPs had voted in from home and in the House of Commons, where the Prime Minister sought to reassure MPs that the measures – which are due to expire on December 2 – should enable shops and businesses to reopen in time for the run-up to Christmas.
He acknowledged however that it would depend on getting the R number – the reproduction rate of the virus – back down below 1.
Mr Bristow had launched a survey to find out what the people of the city thought ahead of the vote, asking people to share their thoughts with him on November 1.
He has expressed his concerns of a second national lockdown, urging that the people of Peterborough need more help.
Mr Bristow wrote on his Facebook: "Lockdown has hit people on low incomes the hardest. Those who work shifts in hospitality and retail. It's bad for those living alone, shared renters and those in flats and small houses.
"Peterborough will need help. This is my job and I will fight for our city."
Prime Minister Boris Johnson said: "From Thursday, until the start of December, you must stay at home. You may only leave home for specific reasons, for education, for work if you cannot work from home, for exercise, recreation outdoors from your household or on your own, or with one person from another household. For medical reasons, appointments and to escape injury or harm, to shop for food and essentials or to care for vulnerable people as a volunteer."
Mr Johnson has confirmed that the second lockdown will see the closure of non-essential retail, leisure, entertainment, pubs and restaurants; while schools and essential retail will stay open.
Click and collect services and takeaway and delivery services are allowed to stay open, construction and manufacturing workers are also allowed to continue their day jobs.
Single adult households are allowed to form support bubbles with one other household and children are able to move between homes if parents are separated.
Mr Johnson added: "If you are clinically vulnerable or over the age of 60, you should be especially careful to follow the rules and minimise contact with others. I know how tough shielding was and we will not ask people to shield again in the same way. But we are asking those who are clinically extremely vulnerable to minimise their contact with others."
He continued: "I am under no illusions about how difficult this will be for business who have already had to endure such hardship this year and I am truly, truly sorry for that. That's why we're going to extend the furlough system through November.
"The furlough scheme was a success in the Spring in supporting people and businesses in a critical time. We will not end it. We will extend furlough until December. There will be some differences compared to March."
Mr Johnson warned that Christmas will be different this year, adding: "It's my sincere hope and belief that by taking tough action now we can allow families across the country to be together."
Boris Johnson insisted the new national lockdown is not the same as the "full scale lockdown" of the spring.